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Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes

Autologous chondrocyte implantation (ACI) is a procedure used to treat articular cartilage injuries and prevent the onset of post-traumatic osteoarthritis. In vitro expansion of chondrocytes, a necessary step in ACI, results in the generation of senescent cells that adversely affect the quality and...

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Detalles Bibliográficos
Autores principales:	Huang, Yuzhao, He, Yuchen, Makarcyzk, Meagan J., Lin, Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116695/ https://www.ncbi.nlm.nih.gov/pubmed/33996787 http://dx.doi.org/10.3389/fbioe.2021.677576

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