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DNA damage and repair in the differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

The review summarizes literature data on the role of DNA breaks and DNA repair in the differentiation of pluripotent stem cells (PSC) and connective cell lineages. PSC, including embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC), are rapidly dividing cells with highly active DNA d...

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Detalles Bibliográficos
Autores principales: Sjakste, Nikolajs, Riekstiņa, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116775/
https://www.ncbi.nlm.nih.gov/pubmed/33942598
http://dx.doi.org/10.4081/ejh.2021.3236

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