A novel substitution in NS5A enhances the resistance of hepatitis C virus genotype 3 to daclatasvir

Hepatitis C virus (HCV) genotype 3 presents a high level of both baseline and acquired resistance to direct-acting antivirals (DAAs), particularly those targeting the NS5A protein. To understand this resistance we studied a cohort of Brazilian patients treated with the NS5A DAA, daclatasvir and the...

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Detalles Bibliográficos
Autores principales: Fernandes Campos, Guilherme Rodrigues, Ward, Joseph, Chen, Shucheng, Bittar, Cintia, Vilela Rodrigues, João Paulo, Martinelli, Ana de Lourdes Candolo, Souza, Fernanda Fernandes, Pereira, Leonardo Régis Leira, Rahal, Paula, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116786/
https://www.ncbi.nlm.nih.gov/pubmed/33141008
http://dx.doi.org/10.1099/jgv.0.001496

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