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Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy
Background: Sodium–glucose cotransporter-2 (SGLT2) inhibitors have been shown to decrease the adverse cardiac events and risks of cardiovascular mortality among patients with or without diabetes, which has made these drugs promising treatment options for patients with chronic heart failure. Cardiac...
Autores principales: | Ren, Changzhen, Sun, Kaiqiang, Zhang, Yanda, Hu, Yangxi, Hu, Bowen, Zhao, Jian, He, Zhiqing, Ding, Ru, Wang, Weizhong, Liang, Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116890/ https://www.ncbi.nlm.nih.gov/pubmed/33995090 http://dx.doi.org/10.3389/fphar.2021.664181 |
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