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Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study
Background: National long-term care development requires updated epidemiological data related to frailty. We aimed to find the prevalence of frailty and its associated factors among Indonesian elderly. Methods: We conducted first-phase cross-sectional analysis of Indonesia Longitudinal Aging Study (...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116892/ https://www.ncbi.nlm.nih.gov/pubmed/33996862 http://dx.doi.org/10.3389/fmed.2021.658580 |
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author | Setiati, Siti Soejono, Czeresna Heriawan Harimurti, Kuntjoro Dwimartutie, Noto Aryana, I. G. P. Suka Sunarti, Sri Budiningsih, Fatichati Mulyana, Roza Dwipa, Lazuardhi Sudarso, Agus Rensa, Rensa Istanti, Rahmi Azwar, Muhammad Khifzhon Marsigit, Jessica |
author_facet | Setiati, Siti Soejono, Czeresna Heriawan Harimurti, Kuntjoro Dwimartutie, Noto Aryana, I. G. P. Suka Sunarti, Sri Budiningsih, Fatichati Mulyana, Roza Dwipa, Lazuardhi Sudarso, Agus Rensa, Rensa Istanti, Rahmi Azwar, Muhammad Khifzhon Marsigit, Jessica |
author_sort | Setiati, Siti |
collection | PubMed |
description | Background: National long-term care development requires updated epidemiological data related to frailty. We aimed to find the prevalence of frailty and its associated factors among Indonesian elderly. Methods: We conducted first-phase cross-sectional analysis of Indonesia Longitudinal Aging Study (INALAS) data collected from community-dwelling outpatients aged 60 years and older without acute illness in nine geriatric service care centres. Descriptive, bivariate and multivariate analyses were conducted. Results: Among 908 elderly in this study, 15.10% were robust, 66.20% were pre-frail, and 18.70% were frail. Functional dependence was associated with frailty among Indonesian elderly (OR 5.97, 95% CI 4.04–8.80). Being depressed and at risk for malnutrition were also associated with frailty with OR 2.54, 95% CI 1.56–4.12, and OR 2.56, 95% CI 1.68–3.90, respectively. Prior history of fall (OR 1.77, 95% CI 1.16–2.72) and hospitalization (OR 1.46, 95% CI 0.97–2.20) in the previous 12 months were associated with frailty. There is also significant association between poly pharmacy and frailty (OR 2.42, 95% CI 1.50–3.91). Conclusion: Approximately one in five Indonesian community-dwelling elderly was frail. Frailty is associated with functional dependence, being at risk for malnutrition or being malnourished, depression, history of fall, history of hospitalization, and poly pharmacy. There may be bidirectional relationships between the risk factors and frailty. The development of long-term care in Indonesia should be considered, without forcing the elderly who need it. |
format | Online Article Text |
id | pubmed-8116892 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81168922021-05-14 Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study Setiati, Siti Soejono, Czeresna Heriawan Harimurti, Kuntjoro Dwimartutie, Noto Aryana, I. G. P. Suka Sunarti, Sri Budiningsih, Fatichati Mulyana, Roza Dwipa, Lazuardhi Sudarso, Agus Rensa, Rensa Istanti, Rahmi Azwar, Muhammad Khifzhon Marsigit, Jessica Front Med (Lausanne) Medicine Background: National long-term care development requires updated epidemiological data related to frailty. We aimed to find the prevalence of frailty and its associated factors among Indonesian elderly. Methods: We conducted first-phase cross-sectional analysis of Indonesia Longitudinal Aging Study (INALAS) data collected from community-dwelling outpatients aged 60 years and older without acute illness in nine geriatric service care centres. Descriptive, bivariate and multivariate analyses were conducted. Results: Among 908 elderly in this study, 15.10% were robust, 66.20% were pre-frail, and 18.70% were frail. Functional dependence was associated with frailty among Indonesian elderly (OR 5.97, 95% CI 4.04–8.80). Being depressed and at risk for malnutrition were also associated with frailty with OR 2.54, 95% CI 1.56–4.12, and OR 2.56, 95% CI 1.68–3.90, respectively. Prior history of fall (OR 1.77, 95% CI 1.16–2.72) and hospitalization (OR 1.46, 95% CI 0.97–2.20) in the previous 12 months were associated with frailty. There is also significant association between poly pharmacy and frailty (OR 2.42, 95% CI 1.50–3.91). Conclusion: Approximately one in five Indonesian community-dwelling elderly was frail. Frailty is associated with functional dependence, being at risk for malnutrition or being malnourished, depression, history of fall, history of hospitalization, and poly pharmacy. There may be bidirectional relationships between the risk factors and frailty. The development of long-term care in Indonesia should be considered, without forcing the elderly who need it. Frontiers Media S.A. 2021-04-29 /pmc/articles/PMC8116892/ /pubmed/33996862 http://dx.doi.org/10.3389/fmed.2021.658580 Text en Copyright © 2021 Setiati, Soejono, Harimurti, Dwimartutie, Aryana, Sunarti, Budiningsih, Mulyana, Dwipa, Sudarso, Rensa, Istanti, Azwar and Marsigit. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Setiati, Siti Soejono, Czeresna Heriawan Harimurti, Kuntjoro Dwimartutie, Noto Aryana, I. G. P. Suka Sunarti, Sri Budiningsih, Fatichati Mulyana, Roza Dwipa, Lazuardhi Sudarso, Agus Rensa, Rensa Istanti, Rahmi Azwar, Muhammad Khifzhon Marsigit, Jessica Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
title | Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
title_full | Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
title_fullStr | Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
title_full_unstemmed | Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
title_short | Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
title_sort | frailty and its associated risk factors: first phase analysis of multicentre indonesia longitudinal aging study |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116892/ https://www.ncbi.nlm.nih.gov/pubmed/33996862 http://dx.doi.org/10.3389/fmed.2021.658580 |
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