YML018C protein localizes to the vacuolar membrane independently of Atg27p

The function of the budding yeast YML018C protein remains to be determined. High-throughput studies have reported that the YML018C protein localizes to the vacuolar membrane and physically interacts with the autophagy-related protein Atg27p. While this evidence suggests a potential role for this unc...

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Detalles Bibliográficos
Autores principales: Sturgeon, Candyce M., Zanghi, Nicholas, Smith, Hannah M., Davis, Emily K., Robinson, Meaghan R., Cabrera, Elizabeth, Holbrook, Molly C., Segarra, Verónica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116935/
https://www.ncbi.nlm.nih.gov/pubmed/33997660
http://dx.doi.org/10.17912/micropub.biology.000391
Descripción
Sumario:The function of the budding yeast YML018C protein remains to be determined. High-throughput studies have reported that the YML018C protein localizes to the vacuolar membrane and physically interacts with the autophagy-related protein Atg27p. While this evidence suggests a potential role for this uncharacterized protein in the process of autophagy, the function of this putative interaction remains uncharacterized. In this micropublication, we report our finding that the localization of the YML018C protein to the vacuolar membrane does not require Atg27p.

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