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Next Generation Sequencing for Detecting Somatic FAS Mutations in Patients With Autoimmune Lymphoproliferative Syndrome

Autoimmune lymphoproliferative syndrome (ALPS) is a primary immune regulatory disorder clinically defined by chronic and benign lymphoproliferation, autoimmunity and an increased risk of lymphoma due to a genetic defect in the FAS-FASL apoptotic pathway. Genetic defects associated with ALPS are germ...

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Detalles Bibliográficos
Autores principales:	López-Nevado, Marta, Docampo-Cordeiro, Jorge, Ramos, José T., Rodríguez-Pena, Rebeca, Gil-López, Celia, Sánchez-Ramón, Silvia, Gil-Herrera, Juana, Díaz-Madroñero, María J., Delgado-Martín, María A., Morales-Pérez, Pablo, Paz-Artal, Estela, Magerus, Aude, Rieux-Laucat, Frederic, Allende, Luis M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117005/ https://www.ncbi.nlm.nih.gov/pubmed/33995372 http://dx.doi.org/10.3389/fimmu.2021.656356

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