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Gene Families With Stochastic Exclusive Gene Choice Underlie Cell Adhesion in Mammalian Cells

Exclusive stochastic gene choice combines precision with diversity. This regulation enables most T-cells to express exactly one T-cell receptor isoform chosen from a large repertoire, and to react precisely against diverse antigens. Some cells express two receptor isoforms, revealing the stochastic...

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Detalles Bibliográficos
Autores principales: Iakovlev, Mikhail, Faravelli, Simone, Becskei, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117012/
https://www.ncbi.nlm.nih.gov/pubmed/33996799
http://dx.doi.org/10.3389/fcell.2021.642212