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Case Report: Immune Checkpoint Inhibitor-Induced Exuberant Tumor Inflammation With Accelerated Clinical Deterioration in Metastatic Renal Cell Carcinoma
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy. Nivolumab, an anti-PD-1 monoclonal antibody, markedly improved overall survival in advanced renal cell carcinoma (RCC). However, ICIs can rarely trigger massive inflammation, a phenomenon characterized by rapid acceleration in r...
Autores principales: | Gopalakrishnan, Dharmesh, Jain, Rohit K., Herbst, Laurie, Sikorski, Marcus, Mandava, Silpa, Azabdaftari, Gissou, Xu, Bo, LeVea, Charles, Robillard, Kevin, Ernstoff, Marc S., George, Saby |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117341/ https://www.ncbi.nlm.nih.gov/pubmed/33996609 http://dx.doi.org/10.3389/fonc.2021.679177 |
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