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H3K27M and TERT promoter mutations are poor prognostic factors in surgical cases of adult thalamic high-grade glioma

BACKGROUND: Thalamic high-grade gliomas (HGGs) are rare tumors with a dismal prognosis. H3K27M and telomerase reverse transcriptase promoter (TERTp) mutations reportedly contribute to poor prognoses in HGG cases. We investigated the outcomes of surgically treated adult thalamic HGGs to evaluate the...

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Detalles Bibliográficos
Autores principales:	Osada, Yoshinari, Saito, Ryuta, Shibahara, Ichiyo, Sasaki, Keisuke, Shoji, Takuhiro, Kanamori, Masayuki, Sonoda, Yukihiko, Kumabe, Toshihiro, Watanabe, Mika, Tominaga, Teiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Clinical Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117440/ https://www.ncbi.nlm.nih.gov/pubmed/34013205 http://dx.doi.org/10.1093/noajnl/vdab038

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