Identification of four insertion sites for foreign genes in a pseudorabies virus vector

BACKGROUND: Pseudorabies virus (PRV) is a preferred vector for recombinant vaccine construction. Previously, we generated a TK&gE-deleted PRV (PRV(Δ)(TK&gE−AH02)) based on a virulent PRV AH02LA strain. It was shown to be safe for 1-day-old piglets with maternal PRV antibodies and 4 ~ 5 week-...

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Autores principales: Zhang, Chuanjian, Guo, Shiqi, Guo, Rongli, Chen, Saisai, Zheng, Yating, Xu, Mengwei, Wang, Zhisheng, Liu, Yamei, Wang, Jichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117506/
https://www.ncbi.nlm.nih.gov/pubmed/33980225
http://dx.doi.org/10.1186/s12917-021-02887-w

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