Immunotherapies targeting stimulatory pathways and beyond

Co-stimulatory and co-inhibitory molecules play a critical role in T cell function. Tumor cells escape immune surveillance by promoting immunosuppression. Immunotherapy targeting inhibitory molecules like anti-CTLA-4 and anti-PD-1/PD-L1 were developed to overcome these immunosuppressive effects. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Marin-Acevedo, Julian A., Kimbrough, ErinMarie O., Manochakian, Rami, Zhao, Yujie, Lou, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117548/
https://www.ncbi.nlm.nih.gov/pubmed/33980266
http://dx.doi.org/10.1186/s13045-021-01085-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117548/
https://www.ncbi.nlm.nih.gov/pubmed/33980266
http://dx.doi.org/10.1186/s13045-021-01085-3

Ejemplares similares