Cargando…

Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls

The neurotransmitter serotonin, involved in the regulation of pain and emotion, is critically regulated by the 5‐HT(1A) autoreceptor and the serotonin transporter (5-HTT). Polymorphisms of these genes affect mood and endogenous pain modulation, both demonstrated to be altered in fibromyalgia subject...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ellerbrock, Isabel, Sandström, Angelica, Tour, Jeanette, Fanton, Silvia, Kadetoff, Diana, Schalling, Martin, Jensen, Karin B., Sitnikov, Rouslan, Kosek, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117625/ https://www.ncbi.nlm.nih.gov/pubmed/33980291 http://dx.doi.org/10.1186/s13041-021-00789-4

Ejemplares similares

The translocator protein gene is associated with endogenous pain modulation and the balance between glutamate and γ-aminobutyric acid in fibromyalgia and healthy subjects: a multimodal neuroimaging study
por: Fanton, Silvia, et al.
Publicado: (2022)

Polymorphisms of the μ‐opioid receptor gene influence cerebral pain processing in fibromyalgia
por: Ellerbrock, Isabel, et al.
Publicado: (2020)

The OPRM1 gene and interactions with the 5-HT1a gene regulate conditioned pain modulation in fibromyalgia patients and healthy controls
por: Tour, Jeanette, et al.
Publicado: (2022)

Neural correlates of conditioned pain responses in fibromyalgia subjects indicate preferential formation of new pain associations rather than extinction of irrelevant ones
por: Sandström, Angelica, et al.
Publicado: (2020)

Fibromyalgia patients with elevated levels of anti–satellite glia cell immunoglobulin G antibodies present with more severe symptoms
por: Krock, Emerson, et al.
Publicado: (2023)

Gene-to-gene interactions regulate endogenous pain modulation in fibromyalgia patients and healthy controls—antagonistic effects between opioid and serotonin-related genes
por: Tour, Jeanette, et al.
Publicado: (2017)

Distinct aberrations in cerebral pain processing differentiating patients with fibromyalgia from patients with rheumatoid arthritis
por: Sandström, Angelica, et al.
Publicado: (2022)

Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain — Interleukin-8 in fibromyalgia and interleukin-1 β in rheumatoid arthritis
por: Kosek, Eva, et al.
Publicado: (2015)

Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans
por: Kosek, Eva, et al.
Publicado: (2009)

The role of the serotonergic and GABA system in translational approaches in drug discovery for anxiety disorders
por: Olivier, Jocelien D. A., et al.
Publicado: (2013)

Upregulation of cortical GABA(A) receptor concentration in fibromyalgia
por: Pomares, Florence B., et al.
Publicado: (2020)

Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
por: Galvão-Coelho, Nicole L., et al.
Publicado: (2021)

Multiple spatial scale mapping of time-resolved brain network reconfiguration during evoked pain in patients with rheumatoid arthritis
por: Fanton, Silvia, et al.
Publicado: (2022)

Inducible Gene Manipulations in Serotonergic Neurons
por: Weber, Tillmann, et al.
Publicado: (2009)

Tetracycline Inducible Gene Manipulation in Serotonergic Neurons
por: Weber, Tillmann, et al.
Publicado: (2012)

The effects of a 15-week physical exercise intervention on pain modulation in fibromyalgia: Increased pain-related processing within the cortico-striatal- occipital networks, but no improvement of exercise-induced hypoalgesia
por: Löfgren, Monika, et al.
Publicado: (2023)

[6]-Shogaol Attenuates Oxaliplatin-Induced Allodynia through Serotonergic Receptors and GABA in the Spinal Cord in Mice
por: Kim, Suyong, et al.
Publicado: (2022)

A positive influence of basal ganglia iron concentration on implicit sequence learning
por: Persson, Jonas, et al.
Publicado: (2020)

Attenuation of reserpine-induced fibromyalgia via ROS and serotonergic pathway modulation by fisetin, a plant flavonoid polyphenol
por: Yao, Xianli, et al.
Publicado: (2020)

Sexual dysfunction, mood, anxiety, and personality disorders in female patients with fibromyalgia
por: Kayhan, Fatih, et al.
Publicado: (2016)

The Vastus Lateralis Muscle Interstitium Proteome Changes after an Acute Nociception in Patients with Fibromyalgia Compared to Healthy Subjects—A Microdialysis Study
por: Ghafouri, Bijar, et al.
Publicado: (2023)

Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val(158)met Polymorphism
por: Jensen, Karin B., et al.
Publicado: (2009)

Association between BDNF Gene Polymorphisms and Serotonergic Activity Using Loudness Dependence of Auditory Evoked Potentials in Healthy Subjects
por: Park, Young-Min, et al.
Publicado: (2013)

Perception of Thermal Pain and the Thermal Grill Illusion Is Associated with Polymorphisms in the Serotonin Transporter Gene
por: Lindstedt, Fredrik, et al.
Publicado: (2011)

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?
por: Middeldorp, C M, et al.
Publicado: (2010)

Genes within the serotonergic system are differentially expressed in human brain
por: Sugden, Karen, et al.
Publicado: (2009)

Human fear reconsolidation and allelic differences in serotonergic and dopaminergic genes
por: Agren, T, et al.
Publicado: (2012)

Inducible Gene Manipulations in Brain Serotonergic Neurons of Transgenic Rats
por: Weber, Tillmann, et al.
Publicado: (2011)

Effects of Naltrexone on Pain Sensitivity and Mood in Fibromyalgia: No Evidence for Endogenous Opioid Pathophysiology
por: Younger, Jarred W., et al.
Publicado: (2009)

Pain-related mood influences pain perception differently in fibromyalgia and multiple sclerosis
por: Borg, Céline, et al.
Publicado: (2014)

Ganoderma lucidum Effects on Mood and Health-Related Quality of Life in Women with Fibromyalgia
por: Pazzi, Francesco, et al.
Publicado: (2020)

(1)H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord
por: Erschbamer, Matthias, et al.
Publicado: (2011)

The Effects of Racial/Ethnic Minority Status on Sleep, Mood Disturbance, and Depression in People with Fibromyalgia
por: Marr, Nicole C, et al.
Publicado: (2020)

Conditioned Pain Modulation Is Associated with Common Polymorphisms in the Serotonin Transporter Gene
por: Lindstedt, Fredrik, et al.
Publicado: (2011)

Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2007)

GABA-A receptor genes do not play a role in genetics of Lesch's typology in Caucasian subjects
por: Grzywacz, Anna, et al.
Publicado: (2012)

Serotonergic Neurons in the Chick Brainstem Express Various Serotonin Receptor Subfamily Genes
por: Fujita, Toshiyuki, et al.
Publicado: (2022)

Association of Serotonergic Pathway Gene Polymorphisms With Behavioral Parameters in Patients With Opioid Dependence
por: Sarkar, Siddharth, et al.
Publicado: (2021)

The Role of Serotonergic Gene Methylation in Regulating Anxiety-Related Personality Traits in Chimpanzees
por: Staes, Nicky, et al.
Publicado: (2022)

The pleiotropic contribution of genes in dopaminergic and serotonergic pathways to addiction and related behavioral traits
por: Antón-Galindo, Ester, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6vufjiibtf60n084glt7jgtqd9