Clinical efficacy of nitric oxide nasal spray (NONS) for the treatment of mild COVID-19 infection

Baek et al.(1) investigated the duration of COVID-19 virus shedding in infected patients and demonstrated that even in patients demonstrating prolonged viral clearance, the virus was no longer viable after 15 days post onset of symptoms. Our study aimed to measure whether nitric oxide nasal spray (N...

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Detalles Bibliográficos
Autores principales: Winchester, Stephen, John, Sarah, Jabbar, Kashif, John, Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117664/
https://www.ncbi.nlm.nih.gov/pubmed/33992687
http://dx.doi.org/10.1016/j.jinf.2021.05.009
Descripción
Sumario:Baek et al.(1) investigated the duration of COVID-19 virus shedding in infected patients and demonstrated that even in patients demonstrating prolonged viral clearance, the virus was no longer viable after 15 days post onset of symptoms. Our study aimed to measure whether nitric oxide nasal spray (NONS) further accelerates this reduction in SARS-CoV-2 RNA load versus a control arm with saline spray. Our study recruited 80 participants who were divided into a NONS treatment arm or a placebo arm to test the efficacy of NONS as a treatment for mild COVID-19 infection.

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