Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report

We report the case of a patient with a complete metastatic adrenal response on Pembrolizumab for metastatic lung cancer. Treatment with a systemic corticosteroid‐induced a time‐dependent progression at his metastatic site. Surprisingly, after stopping the corticosteroid, we observed a new complete r...

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Detalles Bibliográficos
Autores principales: Thomas, Quentin Dominique, Sinoquet, Léa, Maraver, Antonio, Quantin, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117819/
https://www.ncbi.nlm.nih.gov/pubmed/34026127
http://dx.doi.org/10.1002/ccr3.3973
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author Thomas, Quentin Dominique
Sinoquet, Léa
Maraver, Antonio
Quantin, Xavier
author_facet Thomas, Quentin Dominique
Sinoquet, Léa
Maraver, Antonio
Quantin, Xavier
author_sort Thomas, Quentin Dominique
collection PubMed
description We report the case of a patient with a complete metastatic adrenal response on Pembrolizumab for metastatic lung cancer. Treatment with a systemic corticosteroid‐induced a time‐dependent progression at his metastatic site. Surprisingly, after stopping the corticosteroid, we observed a new complete response in long‐term adrenal metastases.
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spelling pubmed-81178192021-05-20 Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report Thomas, Quentin Dominique Sinoquet, Léa Maraver, Antonio Quantin, Xavier Clin Case Rep Case Reports We report the case of a patient with a complete metastatic adrenal response on Pembrolizumab for metastatic lung cancer. Treatment with a systemic corticosteroid‐induced a time‐dependent progression at his metastatic site. Surprisingly, after stopping the corticosteroid, we observed a new complete response in long‐term adrenal metastases. John Wiley and Sons Inc. 2021-03-24 /pmc/articles/PMC8117819/ /pubmed/34026127 http://dx.doi.org/10.1002/ccr3.3973 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Thomas, Quentin Dominique
Sinoquet, Léa
Maraver, Antonio
Quantin, Xavier
Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
title Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
title_full Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
title_fullStr Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
title_full_unstemmed Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
title_short Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
title_sort dissociated response related to corticosteroids in lung cancer treated by immunotherapy: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117819/
https://www.ncbi.nlm.nih.gov/pubmed/34026127
http://dx.doi.org/10.1002/ccr3.3973
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AT maraverantonio dissociatedresponserelatedtocorticosteroidsinlungcancertreatedbyimmunotherapyacasereport
AT quantinxavier dissociatedresponserelatedtocorticosteroidsinlungcancertreatedbyimmunotherapyacasereport

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