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Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy

The COVID-19 pandemic has led to a rise in cases of Guillain-Barré syndrome (GBS). This autoimmune sequela is a manifestation of the neurotropism potential of the virus. At present, knowledge regarding the pathophysiology, clinical features, management and outcomes of the condition is still evolving...

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Autores principales: Garcia, Jao Jarro, Turalde, Christian Wilson, Bagnas, Marjorie Anne, Anlacan, Veeda Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118003/
https://www.ncbi.nlm.nih.gov/pubmed/33975846
http://dx.doi.org/10.1136/bcr-2021-242365
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author Garcia, Jao Jarro
Turalde, Christian Wilson
Bagnas, Marjorie Anne
Anlacan, Veeda Michelle
author_facet Garcia, Jao Jarro
Turalde, Christian Wilson
Bagnas, Marjorie Anne
Anlacan, Veeda Michelle
author_sort Garcia, Jao Jarro
collection PubMed
description The COVID-19 pandemic has led to a rise in cases of Guillain-Barré syndrome (GBS). This autoimmune sequela is a manifestation of the neurotropism potential of the virus. At present, knowledge regarding the pathophysiology, clinical features, management and outcomes of the condition is still evolving. This paper presents the case of a 22-year-old pregnant patient who came in with a history of upper respiratory tract symptoms followed by acroparaesthesia and progressive ascending weakness. She was confirmed to have COVID-19 and GBS and was subsequently managed with intravenous immunoglobulin (IVIg) followed by supportive therapy. To the authors’ knowledge and based on their literature search, this is the first reported case of GBS in a COVID-19 confirmed pregnant patient who received IVIg.
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spelling pubmed-81180032021-05-26 Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy Garcia, Jao Jarro Turalde, Christian Wilson Bagnas, Marjorie Anne Anlacan, Veeda Michelle BMJ Case Rep Case Report The COVID-19 pandemic has led to a rise in cases of Guillain-Barré syndrome (GBS). This autoimmune sequela is a manifestation of the neurotropism potential of the virus. At present, knowledge regarding the pathophysiology, clinical features, management and outcomes of the condition is still evolving. This paper presents the case of a 22-year-old pregnant patient who came in with a history of upper respiratory tract symptoms followed by acroparaesthesia and progressive ascending weakness. She was confirmed to have COVID-19 and GBS and was subsequently managed with intravenous immunoglobulin (IVIg) followed by supportive therapy. To the authors’ knowledge and based on their literature search, this is the first reported case of GBS in a COVID-19 confirmed pregnant patient who received IVIg. BMJ Publishing Group 2021-05-11 /pmc/articles/PMC8118003/ /pubmed/33975846 http://dx.doi.org/10.1136/bcr-2021-242365 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Garcia, Jao Jarro
Turalde, Christian Wilson
Bagnas, Marjorie Anne
Anlacan, Veeda Michelle
Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
title Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
title_full Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
title_fullStr Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
title_full_unstemmed Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
title_short Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
title_sort intravenous immunoglobulin in covid-19 associated guillain–barré syndrome in pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118003/
https://www.ncbi.nlm.nih.gov/pubmed/33975846
http://dx.doi.org/10.1136/bcr-2021-242365
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