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The impact of genetic background and sex on the phenotype of IL-23 induced murine spondyloarthritis

BACKGROUND: Overexpression of IL-23 in adult mice by means of hydrodynamic tail vein injection of IL-23 minicircles has been reported to result in spondyloarthritis-like disease. The impact of genetic background and sex on the disease phenotype in this model has not been investigated. METHODS: We co...

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Detalles Bibliográficos
Autores principales: Haley, Emma K., Matmusaev, Mederbek, Hossain, Imtiyaz N., Davin, Sean, Martin, Tammy M., Ermann, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118278/
https://www.ncbi.nlm.nih.gov/pubmed/33983951
http://dx.doi.org/10.1371/journal.pone.0247149