Optimization, and in vitro and in vivo evaluation of etomidate intravenous lipid emulsion

The aim of this investigation was to develop an etomidate intravenous lipid emulsion (ETM-ILE) and evaluate its properties in vitro and in vivo. Etomidate (ETM) is a hydrophobic drug, and organic solvents must be added to an etomidate injectable solution (ETM-SOL) to aid dissolution, that causes var...

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Detalles Bibliográficos
Autores principales: Geng, Dandan, Li, Yan, Wang, Chunyan, Ren, Bo, Wang, Heping, Wu, Chensi, Zhang, Yirong, Zhao, Linlin, Zhao, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118403/
https://www.ncbi.nlm.nih.gov/pubmed/33960250
http://dx.doi.org/10.1080/10717544.2021.1917729

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