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Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in vitro and in vivo studies

Anti-breast cancer action of novel human carbonic anhydrase IX (hCA IX) inhibitor BSM-0004 has been investigated using in vitro and in vivo models of breast cancer. BSM-0004 was found to be a potent and selective hCA IX inhibitor with a Ki value of 96 nM. In vitro anticancer effect of BSM-0004 was a...

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Detalles Bibliográficos
Autores principales:	Mishra, Chandra Bhushan, Mongre, Raj Kumar, Prakash, Amresh, Jeon, Raok, Supuran, Claudiu T., Lee, Myeong-Sok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118463/ https://www.ncbi.nlm.nih.gov/pubmed/33947294 http://dx.doi.org/10.1080/14756366.2021.1909580

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