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The anchor domain is critical for Piezo1 channel mechanosensitivity

The mechanosensitive channel Piezo1 is a crucial membrane mechanosensor ubiquitously expressed in mammalian cell types. Critical to its function in mechanosensory transduction is its ability to change conformation in response to applied mechanical force. Here, we interrogate the role of the anchor d...

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Detalles Bibliográficos
Autores principales: Vero Li, Jinyuan, D Cox, Charles, Martinac, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118467/
https://www.ncbi.nlm.nih.gov/pubmed/33975519
http://dx.doi.org/10.1080/19336950.2021.1923199