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Has GWAS lost its status as a paragon of open science?

Genomic research led the way in open science, a tradition continued by genome-wide association studies (GWAS)—through the sharing of materials, results, and data. Coordinated quality control procedures also contributed to robust findings. However, recent years have seen declines in GWAS transparency...

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Detalles Bibliográficos
Autores principales: Burt, Callie, Munafò, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118511/
https://www.ncbi.nlm.nih.gov/pubmed/33939687
http://dx.doi.org/10.1371/journal.pbio.3001242
Descripción
Sumario:Genomic research led the way in open science, a tradition continued by genome-wide association studies (GWAS)—through the sharing of materials, results, and data. Coordinated quality control procedures also contributed to robust findings. However, recent years have seen declines in GWAS transparency. Here, we assess some shifts away from open science practices with the aim of stimulating a discussion of these issues.