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Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study
INTRODUCTION: The COVID-19 pandemic is associated with a high incidence of venous thromboembolism questioning the utility of a systematic screening for deep venous thrombosis (DVT) in hospitalised patients. METHODS: In this prospective bicentric controlled study, 4-point ultrasound using a pocket de...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Masson SAS.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118667/ https://www.ncbi.nlm.nih.gov/pubmed/34238510 http://dx.doi.org/10.1016/j.jdmv.2021.05.003 |
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author | Fares, Y. Sinzogan-Eyoum, Y.C. Billoir, P. Bogaert, A. Armengol, G. Alexandre, K. Lammens, J. Grall, M. Levesque, H. Benhamou, Y. Miranda, S. |
author_facet | Fares, Y. Sinzogan-Eyoum, Y.C. Billoir, P. Bogaert, A. Armengol, G. Alexandre, K. Lammens, J. Grall, M. Levesque, H. Benhamou, Y. Miranda, S. |
author_sort | Fares, Y. |
collection | PubMed |
description | INTRODUCTION: The COVID-19 pandemic is associated with a high incidence of venous thromboembolism questioning the utility of a systematic screening for deep venous thrombosis (DVT) in hospitalised patients. METHODS: In this prospective bicentric controlled study, 4-point ultrasound using a pocket device was used to screen for DVT, in patients with SARS-CoV-2 infection and controls admitted for acute medical illness not related to COVID-19 hospitalised in general ward, in order to assess the utility of a routine screening and to estimate the prevalence of VTE among those patients. RESULTS: Between April and May 2020, 135 patients were screened, 69 in the COVID+ group and 66 in the control one. There was no significant difference in the rate of proximal DVT between the two groups (2.2% vs. 1.5%; P = 0.52), despite the high rate of PE diagnosed among COVID-19 infected patients (10.1% vs. 1.5%, P = 0.063). No isolated DVT was detected, 37.5% of PE was associated with DVT. Mortality (7.2% vs. 1.5%) was not different (P = 0.21) between COVID-19 patients and controls. CONCLUSION: The systematic screening for proximal DVT was not found to be relevant among COVID-19 patients hospitalized in general ward despite the increase of VTE among this population. Further studies are needed to confirm the hypothesis of a local pulmonary thrombosis which may lead to new therapeutic targets. |
format | Online Article Text |
id | pubmed-8118667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81186672021-05-14 Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study Fares, Y. Sinzogan-Eyoum, Y.C. Billoir, P. Bogaert, A. Armengol, G. Alexandre, K. Lammens, J. Grall, M. Levesque, H. Benhamou, Y. Miranda, S. J Med Vasc Original Article INTRODUCTION: The COVID-19 pandemic is associated with a high incidence of venous thromboembolism questioning the utility of a systematic screening for deep venous thrombosis (DVT) in hospitalised patients. METHODS: In this prospective bicentric controlled study, 4-point ultrasound using a pocket device was used to screen for DVT, in patients with SARS-CoV-2 infection and controls admitted for acute medical illness not related to COVID-19 hospitalised in general ward, in order to assess the utility of a routine screening and to estimate the prevalence of VTE among those patients. RESULTS: Between April and May 2020, 135 patients were screened, 69 in the COVID+ group and 66 in the control one. There was no significant difference in the rate of proximal DVT between the two groups (2.2% vs. 1.5%; P = 0.52), despite the high rate of PE diagnosed among COVID-19 infected patients (10.1% vs. 1.5%, P = 0.063). No isolated DVT was detected, 37.5% of PE was associated with DVT. Mortality (7.2% vs. 1.5%) was not different (P = 0.21) between COVID-19 patients and controls. CONCLUSION: The systematic screening for proximal DVT was not found to be relevant among COVID-19 patients hospitalized in general ward despite the increase of VTE among this population. Further studies are needed to confirm the hypothesis of a local pulmonary thrombosis which may lead to new therapeutic targets. Published by Elsevier Masson SAS. 2021-07 2021-05-14 /pmc/articles/PMC8118667/ /pubmed/34238510 http://dx.doi.org/10.1016/j.jdmv.2021.05.003 Text en © 2021 Published by Elsevier Masson SAS. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Article Fares, Y. Sinzogan-Eyoum, Y.C. Billoir, P. Bogaert, A. Armengol, G. Alexandre, K. Lammens, J. Grall, M. Levesque, H. Benhamou, Y. Miranda, S. Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study |
title | Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study |
title_full | Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study |
title_fullStr | Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study |
title_full_unstemmed | Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study |
title_short | Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study |
title_sort | systematic screening for a proximal dvt in covid-19 hospitalized patients: results of a comparative study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118667/ https://www.ncbi.nlm.nih.gov/pubmed/34238510 http://dx.doi.org/10.1016/j.jdmv.2021.05.003 |
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