Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling

Central neurocytoma (CN) has been known as a benign neuronal tumor. In rare cases, CN undergoes malignant transformation to glioblastomas (GBM). Here we examined its cellular origin by characterizing differentiation potential and gene expression of CN-spheroids. First, we demonstrate that both CN ti...

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Detalles Bibliográficos
Autores principales: Shin, Hye Young, Han, Kyung-Seok, Park, Hyung Woo, Hong, Yun Hwa, Kim, Yona, Moon, Hyo Eun, Park, Kwang Woo, Park, Hye Ran, Lee, C. Justin, Lee, Kiyoung, Kim, Sang Jeong, Heo, Man Seung, Park, Sung-Hye, Kim, Dong Gyu, Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118755/
https://www.ncbi.nlm.nih.gov/pubmed/33972466
http://dx.doi.org/10.5607/en21004

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