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Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair
After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndrome (GI-ARS) lethality. While repurposing leukemia...
Autores principales: | Rotolo, Jimmy A., Fong, Chii Shyang, Bodo, Sahra, Nagesh, Prashanth K.B., Fuller, John, Sharma, Thivashnee, Piersigilli, Alessandra, Zhang, Zhigang, Fuks, Zvi, Singh, Vijay K., Kolesnick, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119204/ https://www.ncbi.nlm.nih.gov/pubmed/33724956 http://dx.doi.org/10.1172/jci.insight.145380 |
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