Gut-derived acetate promotes B10 cells with antiinflammatory effects

Autoimmune diseases are characterized by a breakdown of immune tolerance partly due to environmental factors. The short-chain fatty acid acetate, derived mostly from gut microbial fermentation of dietary fiber, promotes antiinflammatory Tregs and protects mice from type 1 diabetes, colitis, and alle...

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Detalles Bibliográficos
Autores principales: Daïen, C.I., Tan, J., Audo, R., Mielle, J., Quek, L.E., Krycer, J.R., Angelatos, A., Duraes, M., Pinget, G., Ni, D., Robert, R., Alam, M.J., Amian, M.C.B., Sierro, F., Parmar, A., Perkins, G., Hoque, S., Gosby, A.K., Simpson, S.J., Ribeiro, R.V., Mackay, C.R., Macia, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119207/
https://www.ncbi.nlm.nih.gov/pubmed/33729999
http://dx.doi.org/10.1172/jci.insight.144156

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