The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients

Several reports showed SARS-CoV-2 rapid antigen tests (RATs) performances among COVID-19 symptomatic subjects in outpatient settings during periods of highest incidence of infections and high rates of hospital admissions, but few data are present for asymptomatic patients. We investigated the role o...

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Autores principales: Caruana, G., Lebrun, L.-L., Aebischer, O., Opota, O., Urbano, L., de Rham, M., Marchetti, O., Greub, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
New Technologies for Infectious and Tropical Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119292/
https://www.ncbi.nlm.nih.gov/pubmed/34007453
http://dx.doi.org/10.1016/j.nmni.2021.100899
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author Caruana, G.
Lebrun, L.-L.
Aebischer, O.
Opota, O.
Urbano, L.
de Rham, M.
Marchetti, O.
Greub, G.
author_facet Caruana, G.
Lebrun, L.-L.
Aebischer, O.
Opota, O.
Urbano, L.
de Rham, M.
Marchetti, O.
Greub, G.
author_sort Caruana, G.
collection PubMed
description Several reports showed SARS-CoV-2 rapid antigen tests (RATs) performances among COVID-19 symptomatic subjects in outpatient settings during periods of highest incidence of infections and high rates of hospital admissions, but few data are present for asymptomatic patients. We investigated the role of RATs in an emergency department, as a novel screening tool before admission for COVID-19 asymptomatic patients. A total of 116 patients were screened on admission in a 250-bed community hospital in Morges, Switzerland. RAT detected 2/7 RT-PCR-positive patients and delivered two false-positive results. These data suggest the non-fiability of RATs screening in this clinical scenario.
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spelling pubmed-81192922021-05-14 The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients Caruana, G. Lebrun, L.-L. Aebischer, O. Opota, O. Urbano, L. de Rham, M. Marchetti, O. Greub, G. New Microbes New Infect New Technologies for Infectious and Tropical Diseases Several reports showed SARS-CoV-2 rapid antigen tests (RATs) performances among COVID-19 symptomatic subjects in outpatient settings during periods of highest incidence of infections and high rates of hospital admissions, but few data are present for asymptomatic patients. We investigated the role of RATs in an emergency department, as a novel screening tool before admission for COVID-19 asymptomatic patients. A total of 116 patients were screened on admission in a 250-bed community hospital in Morges, Switzerland. RAT detected 2/7 RT-PCR-positive patients and delivered two false-positive results. These data suggest the non-fiability of RATs screening in this clinical scenario. Elsevier 2021-05-14 /pmc/articles/PMC8119292/ /pubmed/34007453 http://dx.doi.org/10.1016/j.nmni.2021.100899 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Technologies for Infectious and Tropical Diseases
Caruana, G.
Lebrun, L.-L.
Aebischer, O.
Opota, O.
Urbano, L.
de Rham, M.
Marchetti, O.
Greub, G.
The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients
title The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients
title_full The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients
title_fullStr The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients
title_full_unstemmed The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients
title_short The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients
title_sort dark side of sars-cov-2 rapid antigen testing: screening asymptomatic patients
topic New Technologies for Infectious and Tropical Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119292/
https://www.ncbi.nlm.nih.gov/pubmed/34007453
http://dx.doi.org/10.1016/j.nmni.2021.100899
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