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Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition

OBJECTIVE: Increased infant birth weight and adiposity are associated with altered risk of adult chronic diseases. The objective was to investigate the association between maternal dietary fat intake during pregnancy and newborn adiposity. STUDY DESIGN: The study included 79 singleton pregnancies. A...

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Autores principales: Damen, Natalie A., Gillingham, Melanie, Hansen, Joyanna G., Thornburg, Kent L., Purnell, Jonathan Q., Marshall, Nicole E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119319/
https://www.ncbi.nlm.nih.gov/pubmed/33510420
http://dx.doi.org/10.1038/s41372-021-00922-0
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author Damen, Natalie A.
Gillingham, Melanie
Hansen, Joyanna G.
Thornburg, Kent L.
Purnell, Jonathan Q.
Marshall, Nicole E.
author_facet Damen, Natalie A.
Gillingham, Melanie
Hansen, Joyanna G.
Thornburg, Kent L.
Purnell, Jonathan Q.
Marshall, Nicole E.
author_sort Damen, Natalie A.
collection PubMed
description OBJECTIVE: Increased infant birth weight and adiposity are associated with altered risk of adult chronic diseases. The objective was to investigate the association between maternal dietary fat intake during pregnancy and newborn adiposity. STUDY DESIGN: The study included 79 singleton pregnancies. Associations between maternal dietary fat intake during each trimester and infant adiposity at birth were assessed. RESULT: Average total grams of maternal total dietary fat and unsaturated fat intake during pregnancy correlated with infant percent body fat after adjusting for potential confounding variables (r=0.23, p=0.045; r =0.24, p=0.037). Maternal average daily intake of total fat, saturated fat, and unsaturated fat during the second trimester of pregnancy were each associated with infant percent body fat (r =0.25, p=0.029; r =0.23, p=0.046; r =0.25, p=0.031; respectively). CONCLUSION: The second trimester of pregnancy is a key time period for fetal adipose tissue metabolic programming and therefore a target for nutritional intervention.
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spelling pubmed-81193192021-07-28 Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition Damen, Natalie A. Gillingham, Melanie Hansen, Joyanna G. Thornburg, Kent L. Purnell, Jonathan Q. Marshall, Nicole E. J Perinatol Article OBJECTIVE: Increased infant birth weight and adiposity are associated with altered risk of adult chronic diseases. The objective was to investigate the association between maternal dietary fat intake during pregnancy and newborn adiposity. STUDY DESIGN: The study included 79 singleton pregnancies. Associations between maternal dietary fat intake during each trimester and infant adiposity at birth were assessed. RESULT: Average total grams of maternal total dietary fat and unsaturated fat intake during pregnancy correlated with infant percent body fat after adjusting for potential confounding variables (r=0.23, p=0.045; r =0.24, p=0.037). Maternal average daily intake of total fat, saturated fat, and unsaturated fat during the second trimester of pregnancy were each associated with infant percent body fat (r =0.25, p=0.029; r =0.23, p=0.046; r =0.25, p=0.031; respectively). CONCLUSION: The second trimester of pregnancy is a key time period for fetal adipose tissue metabolic programming and therefore a target for nutritional intervention. 2021-01-28 2021-05 /pmc/articles/PMC8119319/ /pubmed/33510420 http://dx.doi.org/10.1038/s41372-021-00922-0 Text en http://www.nature.com/authors/editorial_policies/license.html#termsUsers may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Damen, Natalie A.
Gillingham, Melanie
Hansen, Joyanna G.
Thornburg, Kent L.
Purnell, Jonathan Q.
Marshall, Nicole E.
Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition
title Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition
title_full Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition
title_fullStr Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition
title_full_unstemmed Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition
title_short Maternal Dietary Fat Intake During Pregnancy and Newborn Body Composition
title_sort maternal dietary fat intake during pregnancy and newborn body composition
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119319/
https://www.ncbi.nlm.nih.gov/pubmed/33510420
http://dx.doi.org/10.1038/s41372-021-00922-0
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