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SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients

We aimed to evaluate SIGLEC1 (CD169) as a biomarker in multiple sclerosis (MS) and Neuromyelitis optica spectrum disorder (NMOSD) and to evaluate the presence of SIGLEC1(+) myeloid cells in demyelinating diseases. We performed flow cytometry-based measurements of SIGLEC1 expression on monocytes in 8...

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Detalles Bibliográficos
Autores principales:	Ostendorf, Lennard, Dittert, Philipp, Biesen, Robert, Duchow, Ankelien, Stiglbauer, Victoria, Ruprecht, Klemens, Bellmann-Strobl, Judith, Seelow, Dominik, Stenzel, Werner, Niesner, Raluca A., Hauser, Anja E., Paul, Friedemann, Radbruch, Helena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119413/ https://www.ncbi.nlm.nih.gov/pubmed/33986412 http://dx.doi.org/10.1038/s41598-021-89786-0

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