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A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues

Cardiotoxicity of pharmaceutical drugs, industrial chemicals, and environmental toxicants can be severe, even life threatening, which necessitates a thorough evaluation of the human response to chemical compounds. Predicting risks for arrhythmia and sudden cardiac death accurately is critical for de...

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Detalles Bibliográficos
Autores principales: Kofron, Celinda M., Kim, Tae Yun, Munarin, Fabiola, Soepriatna, Arvin H., Kant, Rajeev J., Mende, Ulrike, Choi, Bum-Rak, Coulombe, Kareen L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119415/
https://www.ncbi.nlm.nih.gov/pubmed/33986332
http://dx.doi.org/10.1038/s41598-021-89478-9