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A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues
Cardiotoxicity of pharmaceutical drugs, industrial chemicals, and environmental toxicants can be severe, even life threatening, which necessitates a thorough evaluation of the human response to chemical compounds. Predicting risks for arrhythmia and sudden cardiac death accurately is critical for de...
Autores principales: | Kofron, Celinda M., Kim, Tae Yun, Munarin, Fabiola, Soepriatna, Arvin H., Kant, Rajeev J., Mende, Ulrike, Choi, Bum-Rak, Coulombe, Kareen L. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119415/ https://www.ncbi.nlm.nih.gov/pubmed/33986332 http://dx.doi.org/10.1038/s41598-021-89478-9 |
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