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Detecting the pulmonary trunk in CT scout views using deep learning

For CT pulmonary angiograms, a scout view obtained in anterior–posterior projection is usually used for planning. For bolus tracking the radiographer manually locates a position in the CT scout view where the pulmonary trunk will be visible in an axial CT pre-scan. We automate the task of localizing...

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Autores principales: Demircioğlu, Aydin, Stein, Magdalena Charis, Kim, Moon-Sung, Geske, Henrike, Quinsten, Anton S., Blex, Sebastian, Umutlu, Lale, Nassenstein, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119439/
https://www.ncbi.nlm.nih.gov/pubmed/33986402
http://dx.doi.org/10.1038/s41598-021-89647-w
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author Demircioğlu, Aydin
Stein, Magdalena Charis
Kim, Moon-Sung
Geske, Henrike
Quinsten, Anton S.
Blex, Sebastian
Umutlu, Lale
Nassenstein, Kai
author_facet Demircioğlu, Aydin
Stein, Magdalena Charis
Kim, Moon-Sung
Geske, Henrike
Quinsten, Anton S.
Blex, Sebastian
Umutlu, Lale
Nassenstein, Kai
author_sort Demircioğlu, Aydin
collection PubMed
description For CT pulmonary angiograms, a scout view obtained in anterior–posterior projection is usually used for planning. For bolus tracking the radiographer manually locates a position in the CT scout view where the pulmonary trunk will be visible in an axial CT pre-scan. We automate the task of localizing the pulmonary trunk in CT scout views by deep learning methods. In 620 eligible CT scout views of 563 patients between March 2003 and February 2020 the region of the pulmonary trunk as well as an optimal slice (“reference standard”) for bolus tracking, in which the pulmonary trunk was clearly visible, was annotated and used to train a U-Net predicting the region of the pulmonary trunk in the CT scout view. The networks’ performance was subsequently evaluated on 239 CT scout views from 213 patients and was compared with the annotations of three radiographers. The network was able to localize the region of the pulmonary trunk with high accuracy, yielding an accuracy of 97.5% of localizing a slice in the region of the pulmonary trunk on the validation cohort. On average, the selected position had a distance of 5.3 mm from the reference standard. Compared to radiographers, using a non-inferiority test (one-sided, paired Wilcoxon rank-sum test) the network performed as well as each radiographer (P < 0.001 in all cases). Automated localization of the region of the pulmonary trunk in CT scout views is possible with high accuracy and is non-inferior to three radiographers.
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spelling pubmed-81194392021-05-14 Detecting the pulmonary trunk in CT scout views using deep learning Demircioğlu, Aydin Stein, Magdalena Charis Kim, Moon-Sung Geske, Henrike Quinsten, Anton S. Blex, Sebastian Umutlu, Lale Nassenstein, Kai Sci Rep Article For CT pulmonary angiograms, a scout view obtained in anterior–posterior projection is usually used for planning. For bolus tracking the radiographer manually locates a position in the CT scout view where the pulmonary trunk will be visible in an axial CT pre-scan. We automate the task of localizing the pulmonary trunk in CT scout views by deep learning methods. In 620 eligible CT scout views of 563 patients between March 2003 and February 2020 the region of the pulmonary trunk as well as an optimal slice (“reference standard”) for bolus tracking, in which the pulmonary trunk was clearly visible, was annotated and used to train a U-Net predicting the region of the pulmonary trunk in the CT scout view. The networks’ performance was subsequently evaluated on 239 CT scout views from 213 patients and was compared with the annotations of three radiographers. The network was able to localize the region of the pulmonary trunk with high accuracy, yielding an accuracy of 97.5% of localizing a slice in the region of the pulmonary trunk on the validation cohort. On average, the selected position had a distance of 5.3 mm from the reference standard. Compared to radiographers, using a non-inferiority test (one-sided, paired Wilcoxon rank-sum test) the network performed as well as each radiographer (P < 0.001 in all cases). Automated localization of the region of the pulmonary trunk in CT scout views is possible with high accuracy and is non-inferior to three radiographers. Nature Publishing Group UK 2021-05-13 /pmc/articles/PMC8119439/ /pubmed/33986402 http://dx.doi.org/10.1038/s41598-021-89647-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Demircioğlu, Aydin
Stein, Magdalena Charis
Kim, Moon-Sung
Geske, Henrike
Quinsten, Anton S.
Blex, Sebastian
Umutlu, Lale
Nassenstein, Kai
Detecting the pulmonary trunk in CT scout views using deep learning
title Detecting the pulmonary trunk in CT scout views using deep learning
title_full Detecting the pulmonary trunk in CT scout views using deep learning
title_fullStr Detecting the pulmonary trunk in CT scout views using deep learning
title_full_unstemmed Detecting the pulmonary trunk in CT scout views using deep learning
title_short Detecting the pulmonary trunk in CT scout views using deep learning
title_sort detecting the pulmonary trunk in ct scout views using deep learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119439/
https://www.ncbi.nlm.nih.gov/pubmed/33986402
http://dx.doi.org/10.1038/s41598-021-89647-w
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