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Inhibition of checkpoint kinase 1 potentiates anticancer activity of gemcitabine in bladder cancer cells
Checkpoint kinases (CHKs) are involved in the DNA damage response in many cancer cells. CHK inhibitors have been used in clinical trials in combination with chemotherapeutics; however, their effect against bladder cancer remains unclear. Here, we investigated the efficacy of combining gemcitabine wi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119486/ https://www.ncbi.nlm.nih.gov/pubmed/33986399 http://dx.doi.org/10.1038/s41598-021-89684-5 |