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Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody
Immune-oncology (IO) drug therapy is effective against various types of cancer. Although several, potential, clinical predictive markers have been identified, none so far have proven reliable. Herein we evaluated changes in serum alanine aminotransferase (ALT), which is upregulated by the accumulati...
Autores principales: | Azuma, Takeshi, Takeuchi, Takumi, Matayoshi, Yukihide, Namiki, Shin, Obara, Tetsuya, Imamura, Kazuhiro, Takamori, Mikio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119734/ https://www.ncbi.nlm.nih.gov/pubmed/33986326 http://dx.doi.org/10.1038/s41598-021-88744-0 |
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