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Quantitative Immunohistochemistry to Measure Regional Expression of Nurr1 in the Brain and the Effect of the Nurr1 Heterozygous Genotype

The transcription factor Nurr1 is a member of the steroid hormone nuclear receptor superfamily. Ablation of Nurr1 expression arrests mesencephalic dopamine neuron differentiation while attenuation of Nurr1 in the subiculum and hippocampus impairs learning and memory. Additionally, reduced Nurr1 expr...

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Detalles Bibliográficos
Autores principales: Kummari, Evangel, Guo-Ross, Shirley X., Partington, Heath S., Nutter, Jennifer Makenzie, Eells, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119777/
https://www.ncbi.nlm.nih.gov/pubmed/33994958
http://dx.doi.org/10.3389/fnana.2021.563854