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Expression of Senescence Marker TIGIT Identifies Polyfunctional Donor-Reactive CD4+ T Cells Preferentially Lost After Kidney Transplantation

Development of T-cell hyporesponsiveness to donor antigen may explain the substantial decreased risk for acute rejection in the years following kidney transplantation. The underlying mechanisms of donor-specific hyporesponsiveness (DSH) are largely unknown but may allow for lowering of immunosuppres...

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Detalles Bibliográficos
Autores principales:	van der List, Amy C. J., Litjens, Nicolle H. R., Klepper, Mariska, Betjes, Michiel G. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119878/ https://www.ncbi.nlm.nih.gov/pubmed/33995373 http://dx.doi.org/10.3389/fimmu.2021.656846

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