Defective Interfering Genomes and the Full-Length Viral Genome Trigger RIG-I After Infection With Vesicular Stomatitis Virus in a Replication Dependent Manner

Replication competent vesicular stomatitis virus (VSV) is the basis of a vaccine against Ebola and VSV strains are developed as oncolytic viruses. Both functions depend on the ability of VSV to induce adequate amounts of interferon-α/β. It is therefore important to understand how VSV triggers interf...

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Detalles Bibliográficos
Autores principales: Linder, Andreas, Bothe, Viktoria, Linder, Nicolas, Schwarzlmueller, Paul, Dahlström, Frank, Bartenhagen, Christoph, Dugas, Martin, Pandey, Dharmendra, Thorn-Seshold, Julia, Boehmer, Daniel F. R., Koenig, Lars M., Kobold, Sebastian, Schnurr, Max, Raedler, Johannes, Spielmann, Giulia, Karimzadeh, Hadi, Schmidt, Andreas, Endres, Stefan, Rothenfusser, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119886/
https://www.ncbi.nlm.nih.gov/pubmed/33995343
http://dx.doi.org/10.3389/fimmu.2021.595390

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