Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis

Dysfunction of the circadian clock has been implicated in the pathogenesis of cardiovascular disease. The CLOCK protein is a core molecular component of the circadian oscillator, so that mice with a mutated Clock gene (Clk/Clk) exhibit abnormal rhythms in numerous physiological processes. However, h...

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Detalles Bibliográficos
Autores principales: Yoshida, Yuya, Matsunaga, Naoya, Nakao, Takaharu, Hamamura, Kengo, Kondo, Hideaki, Ide, Tomomi, Tsutsui, Hiroyuki, Tsuruta, Akito, Kurogi, Masayuki, Nakaya, Michio, Kurose, Hitoshi, Koyanagi, Satoru, Ohdo, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119956/
https://www.ncbi.nlm.nih.gov/pubmed/33986294
http://dx.doi.org/10.1038/s41467-021-23050-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119956/
https://www.ncbi.nlm.nih.gov/pubmed/33986294
http://dx.doi.org/10.1038/s41467-021-23050-x

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