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Targeting epigenetic modulation of cholesterol synthesis as a therapeutic strategy for head and neck squamous cell carcinoma

The histone methyltransferase EZH2 silences gene expression via H3 lysine 27 trimethylation and has been recognized as an important antitumour therapeutic target. However, the clinical application of existing EZH2 inhibitors is not satisfactory for the treatment of solid tumours. To discover novel s...

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Detalles Bibliográficos
Autores principales:	Xu, Xing, Chen, Jun, Li, Yan, Yang, Xiaojie, Wang, Qing, Wen, Yanjun, Yan, Ming, Zhang, Jianjun, Xu, Qin, Wei, Yan, Chen, Wantao, Wang, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119982/ https://www.ncbi.nlm.nih.gov/pubmed/33986254 http://dx.doi.org/10.1038/s41419-021-03760-2

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