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An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors

Modeling human behavior within mathematical models of infectious diseases is a key component to understand and control disease spread. We present a mathematical compartmental model of Susceptible–Infectious–Removed to compare the infected curves given by four different functional forms describing th...

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Autores principales: Cabrera, Maritza, Córdova-Lepe, Fernando, Gutiérrez-Jara, Juan Pablo, Vogt-Geisse, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119989/
https://www.ncbi.nlm.nih.gov/pubmed/33986347
http://dx.doi.org/10.1038/s41598-021-89492-x
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author Cabrera, Maritza
Córdova-Lepe, Fernando
Gutiérrez-Jara, Juan Pablo
Vogt-Geisse, Katia
author_facet Cabrera, Maritza
Córdova-Lepe, Fernando
Gutiérrez-Jara, Juan Pablo
Vogt-Geisse, Katia
author_sort Cabrera, Maritza
collection PubMed
description Modeling human behavior within mathematical models of infectious diseases is a key component to understand and control disease spread. We present a mathematical compartmental model of Susceptible–Infectious–Removed to compare the infected curves given by four different functional forms describing the transmission rate. These depend on the distance that individuals keep on average to others in their daily lives. We assume that this distance varies according to the balance between two opposite thrives: the self-protecting reaction of individuals upon the presence of disease to increase social distancing and their necessity to return to a culturally dependent natural social distance that occurs in the absence of disease. We present simulations to compare results for different society types on point prevalence, the peak size of a first epidemic outbreak and the time of occurrence of that peak, for four different transmission rate functional forms and parameters of interest related to distancing behavior, such as: the reaction velocity of a society to change social distance during an epidemic. We observe the vulnerability to disease spread of close contact societies, and also show that certain social distancing behavior may provoke a small peak of a first epidemic outbreak, but at the expense of it occurring early after the epidemic onset, observing differences in this regard between society types. We also discuss the appearance of temporal oscillations of the four different transmission rates, their differences, and how this oscillatory behavior is impacted through social distancing; breaking the unimodality of the actives-curve produced by the classical SIR-model.
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spelling pubmed-81199892021-05-17 An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors Cabrera, Maritza Córdova-Lepe, Fernando Gutiérrez-Jara, Juan Pablo Vogt-Geisse, Katia Sci Rep Article Modeling human behavior within mathematical models of infectious diseases is a key component to understand and control disease spread. We present a mathematical compartmental model of Susceptible–Infectious–Removed to compare the infected curves given by four different functional forms describing the transmission rate. These depend on the distance that individuals keep on average to others in their daily lives. We assume that this distance varies according to the balance between two opposite thrives: the self-protecting reaction of individuals upon the presence of disease to increase social distancing and their necessity to return to a culturally dependent natural social distance that occurs in the absence of disease. We present simulations to compare results for different society types on point prevalence, the peak size of a first epidemic outbreak and the time of occurrence of that peak, for four different transmission rate functional forms and parameters of interest related to distancing behavior, such as: the reaction velocity of a society to change social distance during an epidemic. We observe the vulnerability to disease spread of close contact societies, and also show that certain social distancing behavior may provoke a small peak of a first epidemic outbreak, but at the expense of it occurring early after the epidemic onset, observing differences in this regard between society types. We also discuss the appearance of temporal oscillations of the four different transmission rates, their differences, and how this oscillatory behavior is impacted through social distancing; breaking the unimodality of the actives-curve produced by the classical SIR-model. Nature Publishing Group UK 2021-05-13 /pmc/articles/PMC8119989/ /pubmed/33986347 http://dx.doi.org/10.1038/s41598-021-89492-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Cabrera, Maritza
Córdova-Lepe, Fernando
Gutiérrez-Jara, Juan Pablo
Vogt-Geisse, Katia
An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
title An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
title_full An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
title_fullStr An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
title_full_unstemmed An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
title_short An SIR-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
title_sort sir-type epidemiological model that integrates social distancing as a dynamic law based on point prevalence and socio-behavioral factors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119989/
https://www.ncbi.nlm.nih.gov/pubmed/33986347
http://dx.doi.org/10.1038/s41598-021-89492-x
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