Anti-HIV-1 ADCC and HIV-1 Env Can Be Partners in Reducing Latent HIV Reservoir

BACKGROUND: Persistence of HIV reservoir even in suppressive ART is the key obstacle in HIV-1 cure. We evaluated the ability of HIV-1 C Env to reactivate the latently infected resting memory CD4 cells and the ability of polyclonal HIV antibodies mediating ADCC to lyse the reactivated targets. METHOD...

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Detalles Bibliográficos
Autores principales: Suryawanshi, Poonam, Bagul, Rajani, Shete, Ashwini, Thakar, Madhuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119992/
https://www.ncbi.nlm.nih.gov/pubmed/33995393
http://dx.doi.org/10.3389/fimmu.2021.663919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119992/
https://www.ncbi.nlm.nih.gov/pubmed/33995393
http://dx.doi.org/10.3389/fimmu.2021.663919

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