Cargando…

The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)

Rationale: The pandemic caused by the novel coronavirus SARS-CoV-2 is advancing rapidly. In particular, the number of severe courses of the disease is still dramatically high. An efficient drug therapy that helps to improve significantly the fatal combination of damages in the airway epithelia, in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schepler, Hadrian, Wang, Xiaohong, Neufurth, Meik, Wang, Shunfeng, Schröder, Heinz C., Müller, Werner E. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120197/ https://www.ncbi.nlm.nih.gov/pubmed/33995653 http://dx.doi.org/10.7150/thno.59535

Ejemplares similares

Acceleration of chronic wound healing by bio-inorganic polyphosphate: In vitro studies and first clinical applications
por: Schepler, Hadrian, et al.
Publicado: (2022)

Biomimetic Alginate/Gelatin Cross-Linked Hydrogels Supplemented with Polyphosphate for Wound Healing Applications
por: Wang, Shunfeng, et al.
Publicado: (2020)

The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations
por: Neufurth, Meik, et al.
Publicado: (2020)

Inorganic Polyphosphate: Coacervate Formation and Functional Significance in Nanomedical Applications
por: Schröder, Heinz C, et al.
Publicado: (2022)

Acceleration of Wound Healing through Amorphous Calcium Carbonate, Stabilized with High-Energy Polyphosphate
por: Wang, Shunfeng, et al.
Publicado: (2023)

Caged Dexamethasone/Quercetin Nanoparticles, Formed of the Morphogenetic Active Inorganic Polyphosphate, are Strong Inducers of MUC5AC
por: Neufurth, Meik, et al.
Publicado: (2021)

Functional importance of coacervation to convert calcium polyphosphate nanoparticles into the physiologically active state
por: Müller, Werner E.G., et al.
Publicado: (2022)

Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core–shell system for drug delivery
por: Müller, Werner E. G., et al.
Publicado: (2020)

Polyphosphate Reverses the Toxicity of the Quasi-Enzyme Bleomycin on Alveolar Endothelial Lung Cells In Vitro †
por: Müller, Werner E. G., et al.
Publicado: (2021)

Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate
por: Wang, Xiaohong, et al.
Publicado: (2017)

Morphogenetic (Mucin Expression) as Well as Potential Anti-Corona Viral Activity of the Marine Secondary Metabolite Polyphosphate on A549 Cells
por: Müller, Werner E. G., et al.
Publicado: (2020)

Restoration of Impaired Metabolic Energy Balance (ATP Pool) and Tube Formation Potential of Endothelial Cells under “high glucose”, Diabetic Conditions by the Bioinorganic Polymer Polyphosphate
por: Wang, Xiaohong, et al.
Publicado: (2017)

Inorganic Polymeric Materials for Injured Tissue Repair: Biocatalytic Formation and Exploitation
por: Schröder, Heinz C., et al.
Publicado: (2022)

A Novel Biomimetic Approach to Repair Enamel Cracks/Carious Damages and to Reseal Dentinal Tubules by Amorphous Polyphosphate
por: Müller, Werner E. G., et al.
Publicado: (2017)

Enhancement of Wound Healing in Normal and Diabetic Mice by Topical Application of Amorphous Polyphosphate. Superior Effect of a Host–Guest Composite Material Composed of Collagen (Host) and Polyphosphate (Guest)
por: Müller, Werner E. G., et al.
Publicado: (2017)

An unexpected biomaterial against SARS-CoV-2: Bio-polyphosphate blocks binding of the viral spike to the cell receptor
por: Müller, Werner E.G., et al.
Publicado: (2021)

Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ
por: Müller, Werner E. G., et al.
Publicado: (2018)

Self-Healing Properties of Bioinspired Amorphous CaCO(3)/Polyphosphate-Supplemented Cement
por: Tolba, Emad, et al.
Publicado: (2020)

Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size
por: Müller, Werner E. G., et al.
Publicado: (2017)

Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein Fragment 25-35
por: Müller, Werner E. G., et al.
Publicado: (2017)

Triple-target stimuli-responsive anti-COVID-19 face mask with physiological virus-inactivating agents
por: Müller, Werner E. G., et al.
Publicado: (2021)

Inorganic Polyphosphates As Storage for and Generator of Metabolic Energy in the Extracellular Matrix
por: Müller, Werner E.G., et al.
Publicado: (2019)

Utilization of metabolic energy in treatment of ocular surface disorders: polyphosphate as an energy source for corneal epithelial cell proliferation
por: Gericke, Adrian, et al.
Publicado: (2019)

In Situ Polyphosphate Nanoparticle Formation in Hybrid Poly(vinyl alcohol)/Karaya Gum Hydrogels: A Porous Scaffold Inducing Infiltration of Mesenchymal Stem Cells
por: Tolba, Emad, et al.
Publicado: (2018)

Transformation of Construction Cement to a Self-Healing Hybrid Binder
por: Müller, Werner E.G., et al.
Publicado: (2019)

The Marine Sponge-Derived Inorganic Polymers, Biosilica and Polyphosphate, as Morphogenetically Active Matrices/Scaffolds for the Differentiation of Human Multipotent Stromal Cells: Potential Application in 3D Printing and Distraction Osteogenesis
por: Wang, Xiaohong, et al.
Publicado: (2014)

The enzyme carbonic anhydrase as an integral component of biogenic Ca-carbonate formation in sponge spicules()
por: Müller, Werner E.G., et al.
Publicado: (2013)

Effect of Bioglass on Growth and Biomineralization of SaOS-2 Cells in Hydrogel after 3D Cell Bioprinting
por: Wang, Xiaohong, et al.
Publicado: (2014)

Biocalcite, a multifunctional inorganic polymer: Building block for calcareous sponge spicules and bioseed for the synthesis of calcium phosphate-based bone
por: Wang, Xiaohong, et al.
Publicado: (2014)

Potentiation of the Cytotoxic Activity of Copper by Polyphosphate on Biofilm-Producing Bacteria: A Bioinspired Approach
por: Müller, Werner E. G., et al.
Publicado: (2012)

The Deep-Sea Natural Products, Biogenic Polyphosphate (Bio-PolyP) and Biogenic Silica (Bio-Silica), as Biomimetic Scaffolds for Bone Tissue Engineering: Fabrication of a Morphogenetically-Active Polymer
por: Wang, Xiaohong, et al.
Publicado: (2013)

Modular Small Diameter Vascular Grafts with Bioactive Functionalities
por: Neufurth, Meik, et al.
Publicado: (2015)

Electrospun bioactive mats enriched with Ca-polyphosphate/retinol nanospheres as potential wound dressing
por: Müller, Werner E.G., et al.
Publicado: (2015)

Inorganic polyphosphate in mammals: where's Wally?
por: Desfougères, Yann, et al.
Publicado: (2020)

Inorganic polyphosphate as an energy source in tumorigenesis
por: Boyineni, Jerusha, et al.
Publicado: (2020)

Inorganic Polyphosphate Modulates TRPM8 Channels
por: Zakharian, Eleonora, et al.
Publicado: (2009)

Signalling properties of inorganic polyphosphate in the mammalian brain
por: Holmström, Kira M., et al.
Publicado: (2013)

Identity and functions of inorganic and inositol polyphosphates in plants
por: Lorenzo‐Orts, Laura, et al.
Publicado: (2019)

The Polyphosphate Kinase Gene ppk2 Is Required for Mycobacterium tuberculosis Inorganic Polyphosphate Regulation and Virulence
por: Chuang, Yu-Min, et al.
Publicado: (2013)

Inorganic polyphosphate occurs in the cell wall of Chlamydomonas reinhardtii and accumulates during cytokinesis
por: Werner, Thomas P, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_hljdbneqvt31a55cd0uijabtbp