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Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer
The treatment for metastatic castration-resistant prostate cancer patients remains a great challenge in the clinic and continuously demands discoveries of new targets and therapies. Here, we assess the function and therapeutic value of SIRT6 in metastatic castration-resistant prostate cancer. Method...
Autores principales: | Han, Qing, Xie, Qian Rueben, Li, Fan, Cheng, Yirui, Wu, Tingyu, Zhang, Yanshuang, Lu, Xin, Wong, Alice S.T., Sha, Jianjun, Xia, Weiliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120217/ https://www.ncbi.nlm.nih.gov/pubmed/33995674 http://dx.doi.org/10.7150/thno.53886 |
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