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Differential Mutation Detection Capability Through Capture-Based Targeted Sequencing in Plasma Samples in Hepatocellular Carcinoma

Circulating tumor DNA (ctDNA) is a promising biomarker for accurate monitoring and less invasive assessment of tumor burden and treatment response. Here, targeted next-generation sequencing (NGS) with a designed gene panel of 176 cancer-relevant genes was used to assess mutations in 90 ctDNA samples...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Xi, Lei, Yu, Rentao, Xu, Huailong, Wu, Min, Huang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120297/
https://www.ncbi.nlm.nih.gov/pubmed/33996539
http://dx.doi.org/10.3389/fonc.2021.596789

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