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Neprilysin inhibition does not alter dynamic of proenkephalin‐A 119‐159 and pro‐substance P in heart failure

AIMS: As NEP degrades many substrates, the specific therapeutic mechanism of NEP inhibition with angiotensin receptor neprilysin inhibitor (ARNi) in heart failure with reduced ejection fraction (HFrEF) is not entirely evident. The aim of this study was to investigate the response of two substrates o...

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Detalles Bibliográficos
Autores principales: Arfsten, Henrike, Goliasch, Georg, Bartko, Philipp E., Prausmüller, Suriya, Spinka, Georg, Cho, Anna, Novak, Johannes, Mascherbauer, Julia, Haslacher, Helmuth, Strunk, Guido, Hülsmann, Martin, Pavo, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120349/
https://www.ncbi.nlm.nih.gov/pubmed/33742565
http://dx.doi.org/10.1002/ehf2.13278