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Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event

AIMS: The aim of this study is to characterize healthcare resource utilization and costs in patients with heart failure with reduced ejection fraction (HFrEF) following a worsening heart failure event. METHODS AND RESULTS: This was a retrospective observational cohort analysis. Patients with HFrEF w...

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Autores principales: Givertz, Michael M., Yang, Mei, Hess, Gregory P., Zhao, Bin, Rai, Ashwin, Butler, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120411/
https://www.ncbi.nlm.nih.gov/pubmed/33689217
http://dx.doi.org/10.1002/ehf2.13155
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author Givertz, Michael M.
Yang, Mei
Hess, Gregory P.
Zhao, Bin
Rai, Ashwin
Butler, Javed
author_facet Givertz, Michael M.
Yang, Mei
Hess, Gregory P.
Zhao, Bin
Rai, Ashwin
Butler, Javed
author_sort Givertz, Michael M.
collection PubMed
description AIMS: The aim of this study is to characterize healthcare resource utilization and costs in patients with heart failure with reduced ejection fraction (HFrEF) following a worsening heart failure event. METHODS AND RESULTS: This was a retrospective observational cohort analysis. Patients with HFrEF were identified from the PINNACLE Registry and linked to a nationwide pharmacy and medical claims database. Worsening heart failure was defined as stable heart failure with a subsequent hospitalization and/or intravenous diuretic therapy. Healthcare resource use and costs in 2015 US dollars were analysed for dispensed prescriptions, outpatient encounters, and hospital encounters. Among 11 064 patients with HFrEF, 3087 (27.9%) experienced a worsening heart failure event during an average follow‐up of 973 days. During the first 30 days after the worsening event, 19.8% of patients had hospital readmissions with heart failure as the primary or secondary diagnosis. During that same time period, mean per patient heart failure‐related healthcare resource use included 1.3 prescriptions, 0.5 practitioner visits, and 0.5 hospital encounters (admissions, observations, or emergency care), for an average total medical cost of $8779 per patient including $5359 in heart failure‐related costs. During the first year following worsening heart failure onset, mean per patient total and heart failure‐related costs were $62 615 and $35 329, respectively. CONCLUSIONS: The economic burden following a worsening heart failure event calls for further review of methods to prevent progressive disease, improve adherence to guideline‐directed therapy, and develop novel treatments and care strategies to moderate further progression.
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spelling pubmed-81204112021-05-21 Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event Givertz, Michael M. Yang, Mei Hess, Gregory P. Zhao, Bin Rai, Ashwin Butler, Javed ESC Heart Fail Original Research Articles AIMS: The aim of this study is to characterize healthcare resource utilization and costs in patients with heart failure with reduced ejection fraction (HFrEF) following a worsening heart failure event. METHODS AND RESULTS: This was a retrospective observational cohort analysis. Patients with HFrEF were identified from the PINNACLE Registry and linked to a nationwide pharmacy and medical claims database. Worsening heart failure was defined as stable heart failure with a subsequent hospitalization and/or intravenous diuretic therapy. Healthcare resource use and costs in 2015 US dollars were analysed for dispensed prescriptions, outpatient encounters, and hospital encounters. Among 11 064 patients with HFrEF, 3087 (27.9%) experienced a worsening heart failure event during an average follow‐up of 973 days. During the first 30 days after the worsening event, 19.8% of patients had hospital readmissions with heart failure as the primary or secondary diagnosis. During that same time period, mean per patient heart failure‐related healthcare resource use included 1.3 prescriptions, 0.5 practitioner visits, and 0.5 hospital encounters (admissions, observations, or emergency care), for an average total medical cost of $8779 per patient including $5359 in heart failure‐related costs. During the first year following worsening heart failure onset, mean per patient total and heart failure‐related costs were $62 615 and $35 329, respectively. CONCLUSIONS: The economic burden following a worsening heart failure event calls for further review of methods to prevent progressive disease, improve adherence to guideline‐directed therapy, and develop novel treatments and care strategies to moderate further progression. John Wiley and Sons Inc. 2021-03-10 /pmc/articles/PMC8120411/ /pubmed/33689217 http://dx.doi.org/10.1002/ehf2.13155 Text en © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research Articles
Givertz, Michael M.
Yang, Mei
Hess, Gregory P.
Zhao, Bin
Rai, Ashwin
Butler, Javed
Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
title Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
title_full Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
title_fullStr Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
title_full_unstemmed Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
title_short Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
title_sort resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120411/
https://www.ncbi.nlm.nih.gov/pubmed/33689217
http://dx.doi.org/10.1002/ehf2.13155
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