Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial

IMPORTANCE: Older and/or frail patients are underrepresented in landmark cancer trials. Tailored research is needed to address this evidence gap. OBJECTIVE: The GO2 randomized clinical trial sought to optimize chemotherapy dosing in older and/or frail patients with advanced gastroesophageal cancer,...

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Autores principales: Hall, Peter S., Swinson, Daniel, Cairns, David A., Waters, Justin S., Petty, Russell, Allmark, Christine, Ruddock, Sharon, Falk, Stephen, Wadsley, Jonathan, Roy, Rajarshi, Tillett, Tania, Nicoll, Jonathan, Cummins, Sebastian, Mano, Joseph, Grumett, Simon, Stokes, Zuzana, Kamposioras, Konstantinos-Velios, Chatterjee, Anirban, Garcia, Angel, Waddell, Tom, Guptal, Kamalnayan, Maisey, Nick, Khan, Mohammed, Dent, Jo, Lord, Simon, Crossley, Ann, Katona, Eszter, Marshall, Helen, Grabsch, Heike I., Velikova, Galina, Ow, Pei Loo, Handforth, Catherine, Howard, Helen, Seymour, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120440/
https://www.ncbi.nlm.nih.gov/pubmed/33983395
http://dx.doi.org/10.1001/jamaoncol.2021.0848

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