Cargando…

Inhibition of Gabrp reduces the differentiation of airway epithelial progenitor cells into goblet cells

Bronchial asthma is an intractable pulmonary disease that affects millions of individuals worldwide, with the overproduction of mucus contributing to high morbidity and mortality. Gamma-aminobutyric acid (GABA) is associated with goblet cell hyperplasia in the lungs of primate models and Club cells...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, An, Zhang, Qiuyang, Wang, Yongmei, Li, Xue, Li, Kuan, Li, Yu, Wang, Jianhai, Li, Li, Chen, Huaiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120639/ https://www.ncbi.nlm.nih.gov/pubmed/34007329 http://dx.doi.org/10.3892/etm.2021.10152

Ejemplares similares

LKB1 deficiency upregulates RELM-α to drive airway goblet cell metaplasia
por: Li, Yu, et al.
Publicado: (2021)

Niche-Dependent Regulation of Lkb1 in the Proliferation of Lung Epithelial Progenitor Cells
por: Ma, Qingwen, et al.
Publicado: (2022)

Nitric oxide hinders club cell proliferation through Gdpd2 during allergic airway inflammation
por: Yue, Qing, et al.
Publicado: (2023)

The role of TGFβ-HGF-Smad4 axis in regulating the proliferation of mouse airway progenitor cells
por: Li, Xue, et al.
Publicado: (2017)

Goblet Cell Differentiation Potential in Human Corneal Limbal Epithelial Progenitor Cells In Vitro
por: Yokoo, Seiichi, et al.
Publicado: (2020)

Airway epithelial regeneration requires autophagy and glucose metabolism
por: Li, Kuan, et al.
Publicado: (2019)

Autophagy Reprograms Alveolar Progenitor Cell Metabolism in Response to Lung Injury
por: Li, Xue, et al.
Publicado: (2020)

The Association of the GABRP Polymorphisms with Systemic Lupus Erythematosus
por: Kim, Hun-Soo, et al.
Publicado: (2015)

The effect of nerve growth factor on differentiation of corneal limbal epithelial cells to conjunctival goblet cells in vitro
por: Li, Weiwei, et al.
Publicado: (2010)

GABRP is a Promising Prognostic Biomarker and Associated with Immune Cell Infiltration in Lung Squamous Cell Carcinoma
por: Fu, Jiding, et al.
Publicado: (2023)

GABRP is a potential prognostic biomarker and correlated with immune infiltration and tumor microenvironment in pancreatic cancer
por: Yang, Yihui, et al.
Publicado: (2022)

GABRP promotes CD44s-mediated gemcitabine resistance in pancreatic cancer
por: Chen, Chen, et al.
Publicado: (2022)

Mucin granule-associated proteins in human bronchial epithelial cells: the airway goblet cell "granulome"
por: Raiford, Kimberly L, et al.
Publicado: (2011)

Reduced Neurog3 Gene Dosage Shifts Enteroendocrine Progenitor Towards Goblet Cell Lineage in the Mouse Intestine
por: Li, Hui Joyce, et al.
Publicado: (2020)

Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer
por: Sung, Hye Youn, et al.
Publicado: (2017)

Elevated GABRP expression is correlated to the excessive autophagy in intrahepatic cholestasis of pregnancy
por: Dong, Ruihong, et al.
Publicado: (2023)

Glutamine Metabolism Is Required for Alveolar Regeneration during Lung Injury
por: Wang, Sisi, et al.
Publicado: (2022)

Changes in progenitors and differentiated epithelial cells of neonatal piglets
por: Yin, Lanmei, et al.
Publicado: (2021)

Anxa4 mediated airway progenitor cell migration promotes distal epithelial cell fate specification
por: Jiang, Kewu, et al.
Publicado: (2018)

Organoid technology and lung injury mouse models evaluating effects of hydroxychloroquine on lung epithelial regeneration
por: Zhao, Fuxiaonan, et al.
Publicado: (2022)

Zebrafish Agr2 Is Required for Terminal Differentiation of Intestinal Goblet Cells
por: Chen, Yi-Chung, et al.
Publicado: (2012)

Maternal Dietary Supplementation with γ-Aminobutyric Acid Alleviated Oxidative Stress in Gestating Sows and Their Offspring by Regulating GABRP
por: Liu, Xiaoyi, et al.
Publicado: (2022)

Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis
por: Hicks-Berthet, Julia, et al.
Publicado: (2021)

MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model
por: Huang, Xuan, et al.
Publicado: (2022)

Mucus threads from surface goblet cells clear particles from the airways
por: Ermund, Anna, et al.
Publicado: (2021)

Goblet cell interactions reorient bundled mucus strands for efficient airway clearance
por: Bos, Meike F, et al.
Publicado: (2023)

Reduced growth and proliferation dynamics of nasal epithelial stem/progenitor cells in nasal polyps in vitro
por: Yu, Xue Min, et al.
Publicado: (2014)

Gastrointestinal Goblet Cell Adenocarcinomas Harbor Distinctive Clinicopathological, Immune, and Genomic Landscape
por: Lin, Dong-Liang, et al.
Publicado: (2021)

Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63
por: Li, Qiuling, et al.
Publicado: (2023)

Adenocarcinoma Ex Goblet Cell Carcinoid of Appendix: Two Case Reports
por: Wang, Yu-Ting, et al.
Publicado: (2017)

SUMOylation of Rho-associated protein kinase 2 induces goblet cell metaplasia in allergic airways
por: Tan, Dan, et al.
Publicado: (2023)

Resolution of LPS-induced airway inflammation and goblet cell hyperplasia is independent of IL-18
por: Harris, J Foster, et al.
Publicado: (2007)

High expression of sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia
por: Xu, Chengyun, et al.
Publicado: (2018)

Goblet Cell Carcinoids of the Appendix
por: Arnold, R, et al.
Publicado: (2006)

Goblet cell carcinoid of the appendix
por: Pahlavan, Payam S, et al.
Publicado: (2005)

Goblet Cell Carcinoids of the Appendix
por: Holt, Nanna, et al.
Publicado: (2013)

Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4
por: Chen, Oliver G., et al.
Publicado: (2021)

The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways
por: Boucherat, Olivier, et al.
Publicado: (2012)

Altered Goblet Cell Differentiation and Surface Mucus Properties in Hirschsprung Disease
por: Thiagarajah, Jay R., et al.
Publicado: (2014)

Distal airway epithelial progenitor cells are radiosensitive to High-LET radiation
por: McConnell, Alicia M., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_or8hntre9c7fmnun7mg5vag0n7