Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion

OPA1, a large GTPase of the dynamin superfamily, mediates fusion of the mitochondrial inner membranes, regulates cristae morphology, and maintains respiratory chain function. Inner membrane–anchored long forms of OPA1 (l-OPA1) are proteolytically processed by the OMA1 or YME1L proteases, acting at c...

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Detalles Bibliográficos
Autores principales: Wang, Ruohan, Mishra, Prashant, Garbis, Spiros D., Moradian, Annie, Sweredoski, Michael J., Chan, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120690/
https://www.ncbi.nlm.nih.gov/pubmed/33237841
http://dx.doi.org/10.1091/mbc.E20-09-0605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120690/
https://www.ncbi.nlm.nih.gov/pubmed/33237841
http://dx.doi.org/10.1091/mbc.E20-09-0605

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