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Upregulated anti-angiogenic miR-424-5p in type 1 diabetes (model of subclinical cardiovascular disease) correlates with endothelial progenitor cells, CXCR1/2 and other parameters of vascular health

BACKGROUND: In spite of clinical progress, cardiovascular disease (CVD) remains the predominant cause of mortality worldwide. Overexpression studies in animals have proven miR-424-5p to have anti-angiogenic properties. As type 1 diabetes mellitus (T1DM) without CVD displays endothelial dysfunction a...

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Detalles Bibliográficos
Autores principales:	Tamara, Alice, Coulson, David J., Latief, Jevi Septyani, Bakhashab, Sherin, Weaver, Jolanta U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120744/ https://www.ncbi.nlm.nih.gov/pubmed/33985567 http://dx.doi.org/10.1186/s13287-021-02332-7

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