IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?

BACKGROUND: Currently, persistent human papillomavirus (HPV) infection has been related in some geographic regions as a risk factor for esophageal squamous cell carcinoma. It results in the immunoexpression of the p16 protein, which has been used as marker of the oncogenic lineage by this etiologica...

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Autores principales: WOELLNER, Luiz Filipe Alkamin, de MEDEIROS, Juliano Smaniotto, RIBAS, Carmen Australia Paredes Marcondes, NASSIF, Paulo Afonso Nunes, RIBAS-FILHO, Jurandir Marcondes, SOBRAL, Ana Cristina Lira, ARIEDE, Bruno Luiz, COSTA, Debora Azeredo Pacheco Dias DA, MALAFAIA, Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121072/
https://www.ncbi.nlm.nih.gov/pubmed/34008702
http://dx.doi.org/10.1590/0102-672020200002e1528
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author WOELLNER, Luiz Filipe Alkamin
de MEDEIROS, Juliano Smaniotto
RIBAS, Carmen Australia Paredes Marcondes
NASSIF, Paulo Afonso Nunes
RIBAS-FILHO, Jurandir Marcondes
SOBRAL, Ana Cristina Lira
ARIEDE, Bruno Luiz
COSTA, Debora Azeredo Pacheco Dias DA
MALAFAIA, Osvaldo
author_facet WOELLNER, Luiz Filipe Alkamin
de MEDEIROS, Juliano Smaniotto
RIBAS, Carmen Australia Paredes Marcondes
NASSIF, Paulo Afonso Nunes
RIBAS-FILHO, Jurandir Marcondes
SOBRAL, Ana Cristina Lira
ARIEDE, Bruno Luiz
COSTA, Debora Azeredo Pacheco Dias DA
MALAFAIA, Osvaldo
author_sort WOELLNER, Luiz Filipe Alkamin
collection PubMed
description BACKGROUND: Currently, persistent human papillomavirus (HPV) infection has been related in some geographic regions as a risk factor for esophageal squamous cell carcinoma. It results in the immunoexpression of the p16 protein, which has been used as marker of the oncogenic lineage by this etiological agent. AIM: To correlate epidemiological aspects of esophageal squamous cell carcinoma with the prevalence of HPV infection. METHODS: Fifty-eight cases were analyzed and submitted to histopathological and immunohistochemical analysis by p16. RESULTS: Of the 58 cases evaluated, 40 were men and 18 women, with a mean age of 63.2 years. p16 immunoexpression was positive in 46.55%. CONCLUSION: The prevalence of HPV infection is high in esophageal squamous cell carcinoma presenting in almost half of the cases (46.55%), without gender differentiation.
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spelling pubmed-81210722021-05-21 IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA? WOELLNER, Luiz Filipe Alkamin de MEDEIROS, Juliano Smaniotto RIBAS, Carmen Australia Paredes Marcondes NASSIF, Paulo Afonso Nunes RIBAS-FILHO, Jurandir Marcondes SOBRAL, Ana Cristina Lira ARIEDE, Bruno Luiz COSTA, Debora Azeredo Pacheco Dias DA MALAFAIA, Osvaldo Arq Bras Cir Dig Original Article BACKGROUND: Currently, persistent human papillomavirus (HPV) infection has been related in some geographic regions as a risk factor for esophageal squamous cell carcinoma. It results in the immunoexpression of the p16 protein, which has been used as marker of the oncogenic lineage by this etiological agent. AIM: To correlate epidemiological aspects of esophageal squamous cell carcinoma with the prevalence of HPV infection. METHODS: Fifty-eight cases were analyzed and submitted to histopathological and immunohistochemical analysis by p16. RESULTS: Of the 58 cases evaluated, 40 were men and 18 women, with a mean age of 63.2 years. p16 immunoexpression was positive in 46.55%. CONCLUSION: The prevalence of HPV infection is high in esophageal squamous cell carcinoma presenting in almost half of the cases (46.55%), without gender differentiation. Colégio Brasileiro de Cirurgia Digestiva 2021-05-14 /pmc/articles/PMC8121072/ /pubmed/34008702 http://dx.doi.org/10.1590/0102-672020200002e1528 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
WOELLNER, Luiz Filipe Alkamin
de MEDEIROS, Juliano Smaniotto
RIBAS, Carmen Australia Paredes Marcondes
NASSIF, Paulo Afonso Nunes
RIBAS-FILHO, Jurandir Marcondes
SOBRAL, Ana Cristina Lira
ARIEDE, Bruno Luiz
COSTA, Debora Azeredo Pacheco Dias DA
MALAFAIA, Osvaldo
IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
title IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
title_full IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
title_fullStr IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
title_full_unstemmed IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
title_short IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
title_sort is there correlation between human papillomavirus (hpv) and esophageal epidermoid carcinoma?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121072/
https://www.ncbi.nlm.nih.gov/pubmed/34008702
http://dx.doi.org/10.1590/0102-672020200002e1528
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